Dehydrodeguelin
Dehydrodeguelin (6a,12a-Dehydrodeguelin) is a nature product that could be isolated from the leaves of Amorpha fruticosa L.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3466-23-7
- 分子式: C23H20O6
- 分子量:392.40
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Astrocyte | IC50 |
>80 μM
Compound: 2
|
Growth inhibition of Nf1 defective and Trp53 defective mouse primary astrocytes after 2 hrs by XTT assay
Growth inhibition of Nf1 defective and Trp53 defective mouse primary astrocytes after 2 hrs by XTT assay
|
[PMID: 26467198] |
| B16 | IC50 |
0.56 μM
Compound: 8
|
Cytotoxicity against mouse B16 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse B16 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 28665590] |
| HepG2 | IC50 |
0.56 μM
Compound: 8
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 28665590] |
| L5178Y | IC50 |
10.2 μM
Compound: 28
|
Cytotoxicity against mouse L5178Y cells by MTT assay
Cytotoxicity against mouse L5178Y cells by MTT assay
|
[PMID: 28075580] |
| Lewis lung carcinoma cell line | IC50 |
0.56 μM
Compound: 8
|
Cytotoxicity against mouse LL/2 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse LL/2 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 28665590] |
| NCI-H1299 | IC50 |
>500 μM
Compound: 12
|
Cytotoxicity against human H1299 cells after 3 days by MTS assay
Cytotoxicity against human H1299 cells after 3 days by MTS assay
|
[PMID: 23186287] |
化学情報
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CAS 番号 3466-23-7
-
分子量 392.40
-
分子式 C23H20O6
-
SMILES
O=C1C2=C(COC3=CC(OC)=C(OC)C=C32)OC4=C5C=CC(C)(C)OC5=CC=C14
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別名
6a,12a-Dehydrodeguelin
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)