DPPE-PEG5000-NHS
DPPE-PEG5000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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- CAS 番号: 355150-30-0
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
The structure of DPPE-PEG-NHS comprises three key components that work synergistically:
DPPE: Acts as a hydrophobic anchor, responsible for firmly embedding the entire molecule into the membrane structure of lipid nanoparticles.
PEG chain: Acts as a hydrophilic spacer arm, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
NHS: Acts as a reaction interface, reacting efficiently with molecules containing primary amino groups (such as antibodies and peptides) under mild conditions to form stable covalent bonds.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 355150-30-0
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SMILES
CCCCCCCCCCCCCCCC(OC[C@@](COP(O)(OCCNC(OCCOC(ON1C(CCC1=O)=O)=O)=O)=O)([H])OC(CCCCCCCCCCCCCCC)=O)=O.[n]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)