Ferroptosis inducer-5
Ferroptosis inducer-5 (compund 20a) is a ferroptosis inducer.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3043764-74-2
- 分子式: C15H14N2O4S
- 分子量:318.35
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Ferroptosis[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HT-1080 | CC50 |
0.14 μM
Compound: 20a
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Cytotoxicity against human HT-1080 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human HT-1080 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
|
[PMID: 39264826] |
| MDA-MB-231 | CC50 |
0.23 μM
Compound: 20a
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Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
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[PMID: 39264826] |
| MEF | CC50 |
0.12 μM
Compound: 20a
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Cytotoxicity against mouse MEF cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against mouse MEF cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
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[PMID: 39264826] |
| NCI-H522 | CC50 |
0.17 μM
Compound: 20a
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Cytotoxicity against human NCI-H522 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human NCI-H522 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
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[PMID: 39264826] |
| NCI-H522 | CC50 |
0.26 μM
Compound: 20a
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Cytotoxicity against human NCI-H522 cells overexpressing GFP-tagged RV assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human NCI-H522 cells overexpressing GFP-tagged RV assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
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[PMID: 39264826] |
| NCI-H522 | CC50 |
1.59 μM
Compound: 20a
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Cytotoxicity against human NCI-H522 cells overexpressing GFP-tagged SLC7A11 assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human NCI-H522 cells overexpressing GFP-tagged SLC7A11 assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
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[PMID: 39264826] |
| U2OS | CC50 |
7.26 μM
Compound: 20a
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Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
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[PMID: 39264826] |
| WI-38 | CC50 |
1.53 μM
Compound: 20a
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Cytotoxicity against human WI-38 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human WI-38 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
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[PMID: 39264826] |
化学情報
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CAS 番号 3043764-74-2
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分子量 318.35
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分子式 C15H14N2O4S
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SMILES
CC1=C(C2=CSC(C#C)=N2)C/C(C1OC(C)=O)=N\OC(C)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Ferroptosis inducer-5 関連分類
HY-169146 関連分類
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