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製品番号: HY-163281

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FSY-OSO2F

FSY-OSO2F is (S)-2-amino-3-(4-((fluorosulfonyl) oxy) phenyl) propanoic acid. The radiolabeled form of FSY-OSO2F, ([¹⁸F]FSY-OSO2F), serves as a PET tracer that is taken up by cancer cells. FSY-OSO2F can be used in research related to cancer and PET imaging.

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CAS 番号: 1839622-49-9
分子式: C₉H₁₀FNO₅S
分子量:263.24

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

FSY-OSO2F 構造式

CAS 番号: 1839622-49-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

FSY-OSO2F radiolabeled with ¹⁸F exhibits time-dependent cellular accumulation in MCF-7 cells. Competitive inhibition assays verify that the resulting [¹⁸F]FSY-OSO2F internalizes via specific amino acid transport systems and retains over 95% radiochemical purity after 120 min of plasma incubation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

FSY-OSO2F radiolabeled with ¹⁸F ([¹⁸F]FSY-OSO2F) (8–11 MBq; single intravenous administration) is utilized for small-animal dynamic PET-CT imaging and static PET blocking experiments in female nude mice bearing MCF-7 breast cancer xenografts, 22Rv1 prostate cancer xenografts, and intracranial U87MG glioblastoma xenografts; normalized time–activity curves can be acquired from tumor regions of interest during dynamic imaging^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 1839622-49-9
分子量 263.24
分子式 C₉H₁₀FNO₅S
SMILES

O=C(O)[C@@H](N)CC1=CC=C(OS(=O)(F)=O)C=C1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (268 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Huang Y, et al. Design of Novel 18F-Labeled Amino Acid Tracers Using Sulfur 18F-Fluoride Exchange Click Chemistry. ACS Med Chem Lett. 2024 Jan 25;15(2):294-301. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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