CDC42EP1 - CDC42 effector protein 1 Gene

Also Known as CEP1; BORG5; MSE55

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 11135

About CDC42EP1

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:37,560,480-37,569,405 (from NCBI)

This gene has 4 transcripts (splice variants), 264 orthologues and 5 paralogues. Ubiquitous expression in stomach (RPKM 41.4), gall bladder (RPKM 17.9) and 24 other tissues.

Summary

CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin Cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008]

CDC42EP1 Products (1)

mRNA Protein Name
NM_152243.3 NP_689449.1 cdc42 effector protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in positive regulation of pseudopodium assembly IDA
IDA: Inferred from direct assay
11035016 GOA
involved in regulation of cell shape IDA
IDA: Inferred from direct assay
11035016 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CDC42EP1 Protein Structure

PBD

PBD: P21-Rho-binding domain (37 - 69)

BORG_CEP

BORG_CEP: Cdc42 effector (115 - 215)

  • 0
  • 100
  • 200
  • 300
  • 391 a.a.
Protein Preferred Names Protein Names

cdc42 effector protein 1

  • 55 kDa bone marrow stromal/endothelial cell protein

CDC42EP1 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
CDC42EP1 Q00587 RHOJ Homo sapiens Q9H4E5
Y2H Prey Pooling
25416956
Intra
CDC42EP1 Q00587 RHOJ Homo sapiens Q9H4E5
Y2H Array
25416956
Intra
CDC42EP1 Q00587 DEF6 Homo sapiens Q9H4E7
Validated Y2H
25416956
Intra
CDC42EP1 Q00587 CDC42 Homo sapiens P60953
Y2H Prey Pooling
25416956
Intra
CDC42EP1 Q00587 CDC42 Homo sapiens P60953
Y2H Pooling
20936779
Cross: Cross-species interaction Intra: Intraspecies interaction

CDC42EP1 抗体

製品番号 製品名 アプリケーション 反応性
HY-P80075 CDC42EP1 Antibody (YA517) WB Human

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS02303 CDC42EP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Canis familiaris CDC42EP1 VGNC VGNC:39000
Felis catus CDC42EP1 VGNC VGNC:83522
Macaca mulatta CDC42EP1 VGNC VGNC:70782
Rattus norvegicus CDC42EP1 RGD RGD:1311131
Mus musculus CDC42EP1 MGD MGI:1929763
Bos taurus CDC42EP1 VGNC VGNC:27072
Others CDC42EP1 NCBI