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  2. CDC42EP1 - CDC42 effector protein 1 Gene

CDC42EP1 - CDC42 effector protein 1 Gene

Homo sapiens

Also known as CEP1; BORG5; MSE55

Gene ID: 11135 | Gene type: protein coding

About CDC42EP1

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:37,560,480-37,569,405 (from NCBI)

This gene has 4 transcripts (splice variants), 264 orthologues and 5 paralogues. Ubiquitous expression in stomach (RPKM 41.4), gall bladder (RPKM 17.9) and 24 other tissues.

Summary

CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin Cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008]

CDC42EP1 Products(1)

mRNA Protein Name
NM_152243.3 NP_689449.1 cdc42 effector protein 1

CDC42EP1 Protein Structure

PBD

PBD: P21-Rho-binding domain (37 - 69)

BORG_CEP

BORG_CEP: Cdc42 effector (115 - 215)

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  • 391 a.a.
Protein Preferred Names Protein Names

cdc42 effector protein 1

55 kDa bone marrow stromal/endothelial cell protein

Orthologs Information

Species Symbol Source ID
Canis familiaris CDC42EP1 VGNC VGNC:39000
Felis catus CDC42EP1 VGNC VGNC:83522
Macaca mulatta CDC42EP1 VGNC VGNC:70782
Rattus norvegicus CDC42EP1 RGD RGD:1311131
Mus musculus CDC42EP1 MGD MGI:1929763
Bos taurus CDC42EP1 VGNC VGNC:27072