FUNDC1 - FUN14 domain containing 1 Gene

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 139341

About FUNDC1

Cytogenetic location: Xp11.3 Genomic coordinates (GRCh38): X:44,523,639-44,542,859 (from NCBI)

This gene has 2 transcripts (splice variants), 248 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 11.4), heart (RPKM 11.0) and 25 other tissues.

Summary

This gene encodes a protein with a FUN14 superfamily domain. The function of the encoded protein is not known. [provided by RefSeq, Sep 2011]

FUNDC1 Products (1)

mRNA Protein Name
NM_173794.4 NP_776155.1 FUN14 domain-containing protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
20562859 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in autophagy of mitochondrion IDA
IDA: Inferred from direct assay
22267086 GOA
acts upstream of or within autophagy of mitochondrion IGI
IGI: Inferred from genetic interaction
22267086 GOA
acts upstream of or within autophagy of mitochondrion IMP
IMP: Inferred from mutant phenotype
22267086 GOA
involved in mitochondrial fusion IGI
IGI: Inferred from genetic interaction
37931419 GOA
involved in mitophagy IGI
IGI: Inferred from genetic interaction
34244144 GOA
involved in response to hypoxia IDA
IDA: Inferred from direct assay
22267086 GOA
acts upstream of or within response to hypoxia IMP
IMP: Inferred from mutant phenotype
22267086 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in mitochondrial outer membrane IDA
IDA: Inferred from direct assay
22267086 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FUNDC1 Protein Structure

FUN14

FUN14: FUN14 family (53 - 154)

  • 0
  • 100
  • 155 a.a.
Protein Preferred Names Protein Names

FUN14 domain-containing protein 1

FUNDC1 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
FUNDC1 Q8IVP5 SLC25A46 Homo sapiens Q96AG3
Y2H Prey Pooling
25416956
Intra
FUNDC1 Q8IVP5 SLC25A46 Homo sapiens Q96AG3
Validated Y2H
25416956
Intra
FUNDC1 Q8IVP5 SLC25A46 Homo sapiens Q96AG3
Y2H Array
25416956
Intra
FUNDC1 Q8IVP5 EHHADH Homo sapiens Q08426
Y2H Array
31515488
Intra
FUNDC1 Q8IVP5 EHHADH Homo sapiens Q08426
Y2H Array
25416956
Intra
FUNDC1 Q8IVP5 EHHADH Homo sapiens Q08426
Y2H Prey Pooling
25416956
Intra
FUNDC1 Q8IVP5 SH3GLB1 Homo sapiens Q9Y371
Y2H Prey Pooling
25416956
Intra
FUNDC1 Q8IVP5 SNX1 Homo sapiens Q13596
Y2H Array
25416956
Intra
FUNDC1 Q8IVP5 TUFM Homo sapiens P49411
Validated Y2H
25416956
Intra
FUNDC1 Q8IVP5 MAP1LC3B Homo sapiens Q9GZQ8
Validated Y2H
25416956
Intra
FUNDC1 Q8IVP5 MAP1LC3B Homo sapiens Q9GZQ8
Y2H Array
25416956
Intra
FUNDC1 Q8IVP5 MAP1LC3B Homo sapiens Q9GZQ8
BiFC
25416956
Intra
FUNDC1 Q8IVP5 MAP1LC3B Homo sapiens Q9GZQ8
Anti Bait CoIP
24671035
Intra
FUNDC1 Q8IVP5 YES1 Homo sapiens P07947
Y2H Prey Pooling
25416956
Intra
FUNDC1 Q8IVP5 YES1 Homo sapiens P07947
Y2H Array
31515488
Intra
FUNDC1 Q8IVP5 SENP2 Homo sapiens Q9HC62
Validated Y2H
25416956
Intra
FUNDC1 Q8IVP5 SENP2 Homo sapiens Q9HC62
Y2H Array
25416956
Intra
FUNDC1 Q8IVP5 GABARAPL2 Homo sapiens P60520
Y2H Array
31515488
Intra
FUNDC1 Q8IVP5 GABARAPL2 Homo sapiens P60520
Validated Y2H
25416956
Intra
FUNDC1 Q8IVP5 MAP1LC3A Homo sapiens Q9H492
Validated Y2H
25416956
Intra
FUNDC1 Q8IVP5 MAP1LC3A Homo sapiens Q9H492
Y2H Prey Pooling
25416956
Intra
FUNDC1 Q8IVP5 MAP1LC3A Homo sapiens Q9H492
Y2H Array
25416956
Intra
FUNDC1 Q8IVP5 CTBP2 Homo sapiens P56545
Y2H Array
25416956
Cross
FUNDC1 Q8IVP5 Ulk1 Mus musculus O70405
Anti Tag CoIP
24671035
Cross: Cross-species interaction Intra: Intraspecies interaction

FUNDC1 抗体

製品番号 製品名 アプリケーション 反応性
HY-P86881 FUNDC1 Antibody (YA6574) WB, IHC-P Human, Rat

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS05145 FUNDC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17720 Fundc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24185 Fundc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Canis familiaris FUNDC1 VGNC VGNC:41007
Bos taurus FUNDC1 VGNC VGNC:29143
Mus musculus FUNDC1 MGD MGI:1919268
Rattus norvegicus FUNDC1 RGD RGD:1563372
Others FUNDC1 NCBI