COMMD3 - COMM domain containing 3 Gene

Also Known as BUP; C10orf8

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 23412

About COMMD3

Cytogenetic location: 10p12.2 Genomic coordinates (GRCh38): 10:22,316,388-22,320,306 (from NCBI)

This gene has 15 transcripts (splice variants) and 193 orthologues. Ubiquitous expression in heart (RPKM 26.0), appendix (RPKM 25.1) and 25 other tissues.

Summary

Predicted to be involved in sodium ion transport. Predicted to be located in extracellular region and ficolin-1-rich granule lumen. [provided by Alliance of Genome Resources, Apr 2022]

COMMD3 Products (1)

mRNA Protein Name
NM_012071.4 NP_036203.1 COMM domain-containing protein 3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
15799966 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

COMMD3 Protein Structure

COMM_domain

COMM_domain: COMM domain (15 - 191)

  • 0
  • 100
  • 195 a.a.
Protein Preferred Names Protein Names

COMM domain-containing protein 3

  • protein Bup

COMMD3 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
COMMD3 Q9UBI1 PIH1D2 Homo sapiens Q8WWB5
Y2H Prey Pooling
32296183
Intra
COMMD3 Q9UBI1 PIH1D2 Homo sapiens Q8WWB5
Y2H Array
32296183
Intra
COMMD3 Q9UBI1 CCDC93 Homo sapiens Q567U6
Pull Down
25355947
Intra
COMMD3 Q9UBI1 CCDC93 Homo sapiens Q567U6
Anti Tag CoIP
33961781
Intra
COMMD3 Q9UBI1 CCDC93 Homo sapiens Q567U6
Anti Tag CoIP
37172566
Intra
COMMD3 Q9UBI1 CCDC93 Homo sapiens Q567U6
Anti Tag CoIP
28514442
Intra
COMMD3 Q9UBI1 CCDC93 Homo sapiens Q567U6
Pull Down
30833792
Intra
COMMD3 Q9UBI1 COMMD1 Homo sapiens Q8N668
Anti Tag CoIP
37172566
Intra
COMMD3 Q9UBI1 COMMD1 Homo sapiens Q8N668
Pull Down
15799966
Intra
COMMD3 Q9UBI1 COMMD1 Homo sapiens Q8N668
Anti Tag CoIP
33961781
Intra
COMMD3 Q9UBI1 COMMD1 Homo sapiens Q8N668
Pull Down
30833792
Intra
COMMD3 Q9UBI1 COMMD2 Homo sapiens Q86X83
Anti Tag CoIP
37172566
Intra
COMMD3 Q9UBI1 COMMD2 Homo sapiens Q86X83
Y2H Prey Pooling
32296183
Intra
COMMD3 Q9UBI1 COMMD2 Homo sapiens Q86X83
Y2H Array
32296183
Intra
COMMD3 Q9UBI1 COMMD2 Homo sapiens Q86X83
Pull Down
30833792
Intra
COMMD3 Q9UBI1 CCDC22 Homo sapiens O60826
Anti Tag CoIP
37172566
Intra
COMMD3 Q9UBI1 CCDC22 Homo sapiens O60826
Pull Down
30833792
Intra
COMMD3 Q9UBI1 COMMD8 Homo sapiens Q9NX08
Pull Down
30833792
Intra
COMMD3 Q9UBI1 COMMD8 Homo sapiens Q9NX08
Anti Tag CoIP
37172566
Intra
COMMD3 Q9UBI1 COMMD8 Homo sapiens Q9NX08
Anti Tag CoIP
33961781
Intra
COMMD3 Q9UBI1 COMMD8 Homo sapiens Q9NX08
Y2H
21900206
Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases Alias
Myopathy, Distal, 4

  • Distal Myopathy With Posterior Leg And Anterior Hand Involvement

  • MPD4

  • Williams Distal Myopathy

  • Distal Muscular Dystrophy 4

  • Distal Abd-Filaminopathy

  • Distal Myopathy 4

  • Myopathy, Distal, Type 4
Opioid Abuse

  • Opioid-Related Disorders
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS03012 COMMD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus COMMD3 VGNC VGNC:27584
Mus musculus COMMD3 MGD MGI:88218
Canis familiaris COMMD3 VGNC VGNC:39494
Rattus norvegicus COMMD3 RGD RGD:735116
Others COMMD3 NCBI