COMMD2 - COMM domain containing 2 Gene

Also Known as HSPC042

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51122

About COMMD2

Cytogenetic location: 3q25.1 Genomic coordinates (GRCh38): 3:149,738,472-149,752,489 (from NCBI)

This gene has 7 transcripts (splice variants) and 190 orthologues. Ubiquitous expression in thyroid (RPKM 7.0), lung (RPKM 6.4) and 25 other tissues.

Summary

Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

COMMD2 Products (1)

mRNA Protein Name
NM_016094.4 NP_057178.2 COMM domain-containing protein 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15799966 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

COMMD2 Protein Structure

COMM_domain

COMM_domain: COMM domain (14 - 188)

  • 0
  • 100
  • 199 a.a.
Protein Preferred Names Protein Names

COMM domain-containing protein 2

COMMD2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
COMMD2 Q86X83 CCDC93 Homo sapiens Q567U6
Anti Tag CoIP
28514442
Intra
COMMD2 Q86X83 CCDC93 Homo sapiens Q567U6
Pull Down
25355947
Intra
COMMD2 Q86X83 CCDC93 Homo sapiens Q567U6
Anti Tag CoIP
33961781
Intra
COMMD2 Q86X83 CCDC93 Homo sapiens Q567U6
Anti Tag CoIP
35271311
Intra
COMMD2 Q86X83 COMMD1 Homo sapiens Q8N668
Anti Tag CoIP
33961781
Intra
COMMD2 Q86X83 COMMD1 Homo sapiens Q8N668
Anti Tag CoIP
37172566
Intra
COMMD2 Q86X83 COMMD1 Homo sapiens Q8N668
Pull Down
15799966
Intra
COMMD2 Q86X83 COMMD1 Homo sapiens Q8N668
Anti Tag CoIP
35271311
Intra
COMMD2 Q86X83 CCDC22 Homo sapiens O60826
Anti Tag CoIP
28514442
Intra
COMMD2 Q86X83 CCDC22 Homo sapiens O60826
Anti Tag CoIP
35271311
Intra
COMMD2 Q86X83 CCDC22 Homo sapiens O60826
Anti Tag CoIP
37172566
Intra
COMMD2 Q86X83 CCDC22 Homo sapiens O60826
Pull Down
23563313
Intra
COMMD2 Q86X83 CCDC22 Homo sapiens O60826
Anti Tag CoIP
33961781
Intra
COMMD2 Q86X83 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
Intra
COMMD2 Q86X83 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
Intra
COMMD2 Q86X83 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
Intra
COMMD2 Q86X83 COMMD3 Homo sapiens Q9UBI1
Anti Tag CoIP
33961781
Intra
COMMD2 Q86X83 COMMD3 Homo sapiens Q9UBI1
Anti Tag CoIP
28514442
Intra
COMMD2 Q86X83 COMMD3 Homo sapiens Q9UBI1
Anti Tag CoIP
37172566
Intra
COMMD2 Q86X83 COMMD3 Homo sapiens Q9UBI1
Validated Y2H
32296183
Intra
COMMD2 Q86X83 COMMD3 Homo sapiens Q9UBI1
GMS
37172566
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03011 COMMD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus COMMD2 VGNC VGNC:102679
Canis familiaris COMMD2 VGNC VGNC:39493
Bos taurus COMMD2 VGNC VGNC:27583
Rattus norvegicus COMMD2 RGD RGD:1588810
Macaca mulatta COMMD2 VGNC VGNC:71341
Mus musculus COMMD2 MGD MGI:1098806
Others COMMD2 NCBI