Mfge8 - milk fat globule EGF and factor V/VIII domain containing Gene

Also Known as AGS; MFGME8; OAcGD3S; MFGMP-E8

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 25277

Summary

Predicted to enable Integrin binding activity; phosphatidylethanolamine binding activity; and phosphatidylserine binding activity. Involved in positive regulation of cell population proliferation and response to estrogen. Predicted to be located in external side of plasma membrane and extracellular space. Predicted to be extrinsic component of plasma membrane. Human ortholog(s) of this gene implicated in temporal arteritis. Orthologous to human MFGE8 (milk fat globule EGF and factor V/VIII domain containing). [provided by Alliance of Genome Resources, Apr 2022]

Mfge8 Products (2)

mRNA Protein Name
NM_001040186.2 NP_001035276.1 lactadherin isoform 1 precursor
NM_012811.3 NP_036943.1 lactadherin isoform 2 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence 参考文献 由来
involved in positive regulation of cell population proliferation IEP
IEP: Inferred from expression pattern
11085522 RGD
involved in response to estrogen IEP
IEP: Inferred from expression pattern
12801995 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lactadherin

  • MFG-E8

  • MFGM

  • O-acetyl GD3 ganglioside synthase

  • O-acetyl disialoganglioside synthase

  • O-acetyltransferase Milk fat glolbule membrane protein

  • O-acetyltransferase milk fat globule membrane protein

  • SED1

  • milk fat globule-EGF factor 8 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS08381 MFGE8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19023 Mfge8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25512 Mfge8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Mfge8 NCBI NCBI:4240