Glyphosate-d2-1
Glyphosate-d2-1 is the deuterium labeled Glyphosate. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2734001-36-4
- 分子式: C3H6D2NO5P
- 分子量:171.09
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 2734001-36-4
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非標識Cas 1071-83-6
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性状 Solid
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分子量 171.09
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分子式 C3H6D2NO5P
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Color White to off-white
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SMILES
OC(C([2H])([2H])NCP(O)(O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
H2O : 13.89 mg/mL (81.19 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Greim H, et al. Evaluation of carcinogenic potential of the herbicide glyphosate, drawing on tumor incidence data from fourteen chronic/carcinogenicity rodent studies. Crit Rev Toxicol. 2015;45(3):185-208. [Content Brief]
[3]. Zhang JW, et al The toxic effects and possible mechanisms of glyphosate on mouse oocytes. Chemosphere. 2019 Dec237:124435. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.8449 mL | 29.2244 mL | 58.4488 mL | 146.1219 mL |
| 5 mM | 1.1690 mL | 5.8449 mL | 11.6898 mL | 29.2244 mL | |
| 10 mM | 0.5845 mL | 2.9224 mL | 5.8449 mL | 14.6122 mL | |
| 15 mM | 0.3897 mL | 1.9483 mL | 3.8966 mL | 9.7415 mL | |
| 20 mM | 0.2922 mL | 1.4612 mL | 2.9224 mL | 7.3061 mL | |
| 25 mM | 0.2338 mL | 1.1690 mL | 2.3380 mL | 5.8449 mL | |
| 30 mM | 0.1948 mL | 0.9741 mL | 1.9483 mL | 4.8707 mL | |
| 40 mM | 0.1461 mL | 0.7306 mL | 1.4612 mL | 3.6530 mL | |
| 50 mM | 0.1169 mL | 0.5845 mL | 1.1690 mL | 2.9224 mL | |
| 60 mM | 0.0974 mL | 0.4871 mL | 0.9741 mL | 2.4354 mL | |
| 80 mM | 0.0731 mL | 0.3653 mL | 0.7306 mL | 1.8265 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Glyphosate-d2-1 関連分類
HY-B0863S2 関連分類
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