Icariside E4
Based on 1 Customer Validation
Icariside E4 is an antinociceptive agent, and can be isolated from Tabebuia roseo-alba. Icariside E4 has peripheral analgesic activity by ATP-sensitive K+ channel-dependent mechanisms. Icariside E4 also has anti-oxidant, anti-Alzheimer and anti-inflammatory effects.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.13%
- CAS 番号: 126253-42-7
- 分子式: C26H34O10
- 分子量:506.54
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保管条件:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Caco-2 | IC50 |
<5 μg/mL
Compound: Icariside E4
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Cytotoxicity against human Caco2 cells after 72 hrs by MTS assay
Cytotoxicity against human Caco2 cells after 72 hrs by MTS assay
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[PMID: 22032697] |
| CCD-18Co | IC50 |
<5 μg/mL
Compound: Icariside E4
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Cytotoxicity against human CCD-18Co cells after 72 hrs by MTS assay
Cytotoxicity against human CCD-18Co cells after 72 hrs by MTS assay
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[PMID: 22032697] |
| HCT-116 | IC50 |
<5 μg/mL
Compound: Icariside E4
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Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay
Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay
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[PMID: 22032697] |
化学情報
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CAS 番号 126253-42-7
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性状 Solid
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分子量 506.54
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分子式 C26H34O10
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Color White to off-white
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SMILES
OC[C@@H]1C2=CC(CCCO)=CC(OC)=C2O[C@@]1([H])C3=CC(OC)=C(C=C3)O[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Veiga TA, et al. Furoquinoline alkaloids isolated from Balfourodendron riedelianum as photosynthetic inhibitors in spinach chloroplasts. J Photochem Photobiol B. 2013 Mar 5;120:36-43. [Content Brief]
[2]. Suh JY, et al. Hypolipogenic effects of Icariside E4 via phosphorylation of AMPK and inhibition of MID1IP1 in HepG2 cells. Phytother Res. 2023 Jan;37(1):7-14. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Icariside E4 関連分類
HY-N9854 関連分類
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