Phenolic glycosides from sugar maple (Acer saccharum) bark

  • J Nat Prod. 2011 Nov 28;74(11):2472-6. doi: 10.1021/np200678n.
Tao Yuan  1 ,  Chunpeng Wan ,  Antonio González-Sarrías ,  Vamsikrishna Kandhi ,  Nadja B Cech ,  Navindra P Seeram
Affiliations
  • 1. Bioactive Botanical Research Laboratory, Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island 02881, USA.
PMID: 22032697 DOI: 10.1021/np200678n
Abstract

Four new phenolic glycosides, saccharumosides A-D (1-4), along with eight known phenolic glycosides, were isolated from the bark of sugar maple (Acer saccharum). The structures of 1-4 were elucidated on the basis of spectroscopic data analysis. All compounds isolated were evaluated for cytotoxicity effects against human colon tumorigenic (HCT-116 and Caco-2) and nontumorigenic (CCD-18Co) cell lines.