KR-26556
KR-26556 is a sulfonamide type hepatitis B virus (HBV) capsid assembly regulator. KR-26556 exhibits anti-HBV activity with an EC50 of 0.04 μM. KR-26556 has favorable safety characteristics. KR-26556 can be used for research on chronic hepatitis B.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2411762-66-6
- 分子式: C18H17F4N3O4S
- 分子量:447.40
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
8.78 μM
Compound: 11; KR-26556
|
Inhibition of human ERG expressed in human HEK293 cells by patch clamp assay
Inhibition of human ERG expressed in human HEK293 cells by patch clamp assay
|
[PMID: 32071684] |
| HepG2 2.2.15 | CC50 |
19.7 μM
Compound: 15; KR-26556
|
Cytotoxicity against human HepG2 2.2.15 cells assessed as reduction in cell viability incubated for 5 days by MTT assay
Cytotoxicity against human HepG2 2.2.15 cells assessed as reduction in cell viability incubated for 5 days by MTT assay
|
[PMID: 33603970] |
化学情報
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CAS 番号 2411762-66-6
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分子量 447.40
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分子式 C18H17F4N3O4S
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SMILES
O=C(NC1=CC(F)=C(F)C(F)=C1)C2=CC(S(=O)(N3CCC(O)CC3)=O)=C(F)C=C2N
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)