LDH-IN-5
LDH-IN-5 is a Lactate Dehydrogenase (LDH) inhibitor with neuroprotective activity. LDH-IN-5 can inhibit cell apoptosis, reduce ROS, MDA production and increases superoxide dismutase (SOD) activity. LDH-IN-5 can be used for the research of neurological disease, such as ischemic stroke.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2768522-31-0
- 分子式: C36H51BrO6
- 分子量:659.69
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
LDH-IN-5 (Compound s6b) (12.5-50 μM, 6h) significantly increases cell viability and reduces LDH release in mouse hippocampal neuron HT22 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:2dpf albino zebrafish models induced by Ponatinib (HY-12047)[1]
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Dosage:125-500 μg/mL
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Administration:18 h
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Result:Showed the thrombosis incidence decreases by 97% in the 125 μg/mL dose group and 77% in the 500 μg/mL dose group.
Showed no zebrafish death or obvious toxicity at 500 μg/mL.
化学情報
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CAS 番号 2768522-31-0
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分子量 659.69
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分子式 C36H51BrO6
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SMILES
CC1(C)[C@@]2(C)[C@H](OC(CCC(O[C@H](C3=CC=C(Br)C=C3C(O[C@H]4[C@@](C5(C)C)(C)CC[C@H]5C4)=O)CCCC)=O)=O)C[C@@H]1CC2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
LDH-IN-5 関連分類
HY-179027 関連分類
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