LY4101174 Antibody
LY4101174 Antibody (15A7.5; ETx-22 Antibody) is an ADC antibody that serves as the antibody component of LY4101174. LY4101174 is an antibody-drug conjugate (ADC) targeting nectin-4 and exhibits broad-spectrum anti-tumor activity. LY4101174 Antibody is applicable to research related to solid tumors.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.46%
- 分子量:144.73 kDa
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Human IgG1 kappa
Human
Nectin-4
LY4101174 Antibody serves as the antibody component of LY4101174, an ADC targeting nectin-4 with broad-spectrum anti-tumor activity. It exerts cytotoxic effects by releasing Exatecan (HY-13631) to inhibit topoisomerase I[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
/ [NCBI]
Nectin-4
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
-
Product Image
ELISA, FACS, Functional assay
化学情報
-
性状 Liquid
-
分子量 144.73 kDa
-
Color Colorless to light yellow
-
SMILES
[LY4101174 Antibody]
-
別名
15A7.5; ETx-22 Antibody
-
輸送条件
Shipping with dry ice.
-
Formulation
Please refer to the lot-specific COA for specific buffer information.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
-
データシート (257 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Inhibitory Antibodies User Guide (603 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
- LY4101174 Antibody
- 15A7.5
- ETx-22 Antibody
- ADC Antibodies
- topoisomerase I inhibitor
- antibody-drug conjugate
- advanced solid tumors
- advanced urothelial cancer
- nectin-4-MMAE antibody-drug conjugate-resistant tumor models
- metastatic solid tumors
- metastatic urothelial cancer
- advanced urothelial carcinoma
- antitumor activity
- nectin-4
- Inhibitor
- inhibitor
- inhibit