MAT2A-IN-12
MAT2A Allosteric inhibitor 2 is a potent and selective MAT2A allosteric inhibitor with an IC50 of 5 nM. MAT2A Allosteric inhibitor 2 shows nanomolar activity (IC50=5 μM) in the the proliferation assay (MTAP-/- cell line).
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- CAS 番号: 631897-75-1
- 分子式: C20H17NO3
- 分子量:319.35
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
4.957 μM
Compound: 17; STL235627
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Antiproliferative activity against MTAP-/- isogenic variant of human HCT-116 cells assessed as inhibition of cell growth by proliferation assay
Antiproliferative activity against MTAP-/- isogenic variant of human HCT-116 cells assessed as inhibition of cell growth by proliferation assay
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[PMID: 37591318] |
| HCT-116 | IC50 |
9.23 μM
Compound: 17; STL235627
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth by proliferation assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth by proliferation assay
|
[PMID: 37591318] |
化学情報
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CAS 番号 631897-75-1
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分子量 319.35
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分子式 C20H17NO3
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SMILES
CC1=CC(OC2=C3C=C(OC)C=C2)=C3C(C4=CC=C(C)C=C4)=[N+]1[O-]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
MAT2A-IN-12 関連分類
HY-155149 関連分類
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