Nampt activator-2
Based on 1 Customer Validation
Nampt activator-2 (compound 34) is a potent NAMPT activator, with EC50 of 0.023 μM. Nampt activator-2 shows moderate activity against CYP2C9 (0.060 μM), 2D6 (0.41 μM) and 2C19 (0.59 μM).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.79%
- CAS 番号: 2237268-90-3
- 分子式: C17H15ClN4O3S
- 分子量:390.84
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Mouse[1]
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Dosage:1 mg/kg iv and 10 mg/kg po
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Administration:IV, PO; once (Pharmacokinetic Analysis)
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Result:Pharmacokinetic Parameters of Nampt activator-2 in mouse[1].
IV (1 mg/kg) PO (10 mg/kg) Cmax (ng/mL) 9550 AUC0-24 (ng/mL∗h) 54463 t1/2 (h) 3.2 CL (mL/min/kg) 3 Vd (L/kg) 0.61 F (%) 80
化学情報
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CAS 番号 2237268-90-3
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性状 Solid
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分子量 390.84
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分子式 C17H15ClN4O3S
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Color Off-white to light yellow
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SMILES
O=C(NCC1=CNN=C1)NC2=CC=C(S(=O)(C3=CC=C(C=C3)Cl)=O)C=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 250 mg/mL (639.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5586 mL | 12.7930 mL | 25.5859 mL | 63.9648 mL |
| 5 mM | 0.5117 mL | 2.5586 mL | 5.1172 mL | 12.7930 mL | |
| 10 mM | 0.2559 mL | 1.2793 mL | 2.5586 mL | 6.3965 mL | |
| 15 mM | 0.1706 mL | 0.8529 mL | 1.7057 mL | 4.2643 mL | |
| 20 mM | 0.1279 mL | 0.6396 mL | 1.2793 mL | 3.1982 mL | |
| 25 mM | 0.1023 mL | 0.5117 mL | 1.0234 mL | 2.5586 mL | |
| 30 mM | 0.0853 mL | 0.4264 mL | 0.8529 mL | 2.1322 mL | |
| 40 mM | 0.0640 mL | 0.3198 mL | 0.6396 mL | 1.5991 mL | |
| 50 mM | 0.0512 mL | 0.2559 mL | 0.5117 mL | 1.2793 mL | |
| 60 mM | 0.0426 mL | 0.2132 mL | 0.4264 mL | 1.0661 mL | |
| 80 mM | 0.0320 mL | 0.1599 mL | 0.3198 mL | 0.7996 mL | |
| 100 mM | 0.0256 mL | 0.1279 mL | 0.2559 mL | 0.6396 mL |
Nampt activator-2 関連分類
HY-148822 関連分類
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