2237268-90-3
Chemical Structure
Nampt activator-2
- CAS No.: 2237268-90-3
- Formula:C17H15ClN4O3S
- Molecular Weight:390.84
IUPAC Name: 1-((1H-pyrazol-4-yl)methyl)-3-(4-((4-chlorophenyl)sulfonyl)phenyl)urea
InChIKey: WIQYSGZABYMFMD-UHFFFAOYSA-N
SMILES: O=C(NCC1=CNN=C1)NC2=CC=C(S(=O)(C3=CC=C(C=C3)Cl)=O)C=C2
Biological Activity: Nampt activator-2 (compound 34) is a potent NAMPT activator, with EC50 of 0.023 μM. Nampt activator-2 shows moderate activity against CYP2C9 (0.060 μM), 2D6 (0.41 μM) and 2C19 (0.59 μM)[1].
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Nampt activator-2 | 98.79% | Nampt activator-2 (compound 34) is a potent NAMPT activator, with EC50 of 0.023 μM. Nampt activator-2 shows moderate activity against CYP2C9 (0.060 μM), 2D6 (0.41 μM) and 2C19 (0.59 μM). | ||||||||||||||||||||
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Keywords