PqsR-IN-2
PqsR-IN-2 (Compound 19) is a potent PqsR (Pseudomonas aeruginosa quorum sensing transcriptional regulator) inhibitor. PqsR-IN-1 attenuates pyocyanin production and has very low cytotoxicity.
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- CAS 番号: 2982271-63-4
- 分子式: C18H20ClN3OS
- 分子量:361.89
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
PqsR[1]
PqsR-IN-2 (Compound 19) inhibits pqs system with IC50 values of 298 ± 182.0 nM and 265 ± 3.4 nM against two different PA strains PAO1-L and PA14, respectively[1].
PqsR-IN-2 significantly reduces pyocyanin production to 36% against a control of 0.1% DMSO at 3 × the IC50 value in P. aeruginosa strain PAO1-L[1].
PqsR-IN-2 (0-100 µM, 16 h) shows no significant toxicity to A549 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:A549 lung epithelial cells
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Concentration:0.1, 1, 12.5, 25, 50, and 100 µM
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Incubation Time:16 h
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Result:Showed no significant toxicity.
化学情報
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CAS 番号 2982271-63-4
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分子量 361.89
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分子式 C18H20ClN3OS
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SMILES
CCCCCCC1=NC(CN2C=NC3=CC=C(C=C3C2=O)Cl)=CS1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
PqsR-IN-2 関連分類
HY-146706 関連分類
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