Propargyl-PEG5-OH
Based on 1 Customer Validation
Propargyl-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.0%
- CAS 番号: 1036204-60-0
- 分子式: C13H24O6
- 分子量:276.33
-
保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
PROTAC Linkers アイソフォーム固有の製品をすべて表示
More
生物活性
|
PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 1036204-60-0
-
性状 Liquid (Density: 1.078 g/cm3)
-
分子量 276.33
-
分子式 C13H24O6
-
Color Colorless to light yellow
-
SMILES
OCCOCCOCCOCCOCCOCC#C
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (361.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (265 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6189 mL | 18.0943 mL | 36.1886 mL | 90.4715 mL |
| 5 mM | 0.7238 mL | 3.6189 mL | 7.2377 mL | 18.0943 mL | |
| 10 mM | 0.3619 mL | 1.8094 mL | 3.6189 mL | 9.0472 mL | |
| 15 mM | 0.2413 mL | 1.2063 mL | 2.4126 mL | 6.0314 mL | |
| 20 mM | 0.1809 mL | 0.9047 mL | 1.8094 mL | 4.5236 mL | |
| 25 mM | 0.1448 mL | 0.7238 mL | 1.4475 mL | 3.6189 mL | |
| 30 mM | 0.1206 mL | 0.6031 mL | 1.2063 mL | 3.0157 mL | |
| 40 mM | 0.0905 mL | 0.4524 mL | 0.9047 mL | 2.2618 mL | |
| 50 mM | 0.0724 mL | 0.3619 mL | 0.7238 mL | 1.8094 mL | |
| 60 mM | 0.0603 mL | 0.3016 mL | 0.6031 mL | 1.5079 mL | |
| 80 mM | 0.0452 mL | 0.2262 mL | 0.4524 mL | 1.1309 mL | |
| 100 mM | 0.0362 mL | 0.1809 mL | 0.3619 mL | 0.9047 mL |