Preparation of L-alpha-phosphatidyl-D-myo-inositol 3-phosphate (3-PIP) and 3,5-bisphosphate (3,5-PIP2)

  • Bioorg Med Chem Lett. 2000 Aug 7;10(15):1711-3. doi: 10.1016/s0960-894x(00)00315-2.
J R Falck  1 ,  U M Krishna ,  J H Capdevila
Affiliations
  • 1. Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas 75390, USA. [email protected]
PMID: 10937730 DOI: 10.1016/s0960-894x(00)00315-2
Abstract

Practical, asymmetric total syntheses of the title Phospholipids from a readily available myo-inositol derivative as well as short chain and cross-linkable aminoether analogues are described.

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