Pyralomicins, novel antibiotics from Microtetraspora spiralis. II. Structure determination

  • J Antibiot (Tokyo). 1996 Jul;49(7):651-6. doi: 10.7164/antibiotics.49.651.
N Kawamura  1 ,  R Sawa ,  Y Takahashi ,  K Isshiki ,  T Sawa ,  H Naganawa ,  T Takeuchi
Affiliations
  • 1. Institute of Microbial Chemistry, Tokyo, Japan.
PMID: 8784427 DOI: 10.7164/antibiotics.49.651
Abstract

Novel Antibiotics, pyralomicins 1a approximately 1d, 2a approximately 2c were isolated from the culture broth of Microtetraspora spiralis MI178-34F18. The structures of pyralomicins were determined by various NMR spectral analyses including 1H-15N HMBC and 13C¿1H¿ NOE difference experiments.

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