SARS-CoV-2-IN-31
Based on 1 Customer Validation
SARS-CoV-2-IN-31 is an effective COVID-19 inhibitor. SARS-CoV-2-IN-31 exhibits excellent to mild activity against various cancer cell lines with IC50 values range from 28.84 to 38.36 μM. SARS-CoV-2-IN-31 can be used for the research of cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.09%
- CAS 番号: 1017691-52-9
- 分子式: C29H28N4O2
- 分子量:464.56
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
IC50: 38.36 μM (MCF-7); 38.46 μM (MDA-MB-231); 28.84 μM (HeLa); 30.62 μM (PC-3); ＞40 μM (Ishikawa)[1]
SARS-CoV-2-IN-31 exhibits antiproliferative activity in five different human cancer cell lines with IC50 values of 38.36 μM (MCF-7), 38.46 μM (MDA-MB-231), 28.84 μM (HeLa), 30.62 μM (PC-3) and ＞40 μM (Ishikawa), respectively[1].
SARS-CoV-2-IN-31 shows comparatively high binding affinity with value of -8.3 Kcal/mole[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1017691-52-9
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性状 Solid
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分子量 464.56
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分子式 C29H28N4O2
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Color Light yellow to yellow
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SMILES
OC1=C(C(C2=C(N(C3=CC=CC=C3)N=C2C)O)C4=CC=C(CC)C=C4)C(C)=NN1C5=CC=CC=C5
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (107.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1526 mL | 10.7629 mL | 21.5257 mL | 53.8144 mL |
| 5 mM | 0.4305 mL | 2.1526 mL | 4.3051 mL | 10.7629 mL | |
| 10 mM | 0.2153 mL | 1.0763 mL | 2.1526 mL | 5.3814 mL | |
| 15 mM | 0.1435 mL | 0.7175 mL | 1.4350 mL | 3.5876 mL | |
| 20 mM | 0.1076 mL | 0.5381 mL | 1.0763 mL | 2.6907 mL | |
| 25 mM | 0.0861 mL | 0.4305 mL | 0.8610 mL | 2.1526 mL | |
| 30 mM | 0.0718 mL | 0.3588 mL | 0.7175 mL | 1.7938 mL | |
| 40 mM | 0.0538 mL | 0.2691 mL | 0.5381 mL | 1.3454 mL | |
| 50 mM | 0.0431 mL | 0.2153 mL | 0.4305 mL | 1.0763 mL | |
| 60 mM | 0.0359 mL | 0.1794 mL | 0.3588 mL | 0.8969 mL | |
| 80 mM | 0.0269 mL | 0.1345 mL | 0.2691 mL | 0.6727 mL | |
| 100 mM | 0.0215 mL | 0.1076 mL | 0.2153 mL | 0.5381 mL |
SARS-CoV-2-IN-31 関連分類
HY-151474 関連分類
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