SB-611812
Based on 1 Customer Validation
SB-611812 is a urotensin II receptor (UTR) antagonist with the potential in the research of cardiovascular disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.92%
- CAS 番号: 345892-71-9
- 分子式: C17H16Cl3F3N2O3S
- 分子量:491.74
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
生物活性
化学情報
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CAS 番号 345892-71-9
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性状 Solid
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分子量 491.74
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分子式 C17H16Cl3F3N2O3S
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Color Light yellow to yellow
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SMILES
O=S(NC1=CC=C(C(OCCN(C)C)=C1)Cl)(C2=C(C=C(C(F)(F)F)C=C2Cl)Cl)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 16.67 mg/mL (33.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Rakowski E, et al. A role for urotensin II in restenosis following balloon angioplasty: use of a selective UT receptor blocker. J Mol Cell Cardiol. 2005 Nov;39(5):785-91. [Content Brief]
[2]. Cosenzi A. Non peptidic urotensin II antagonists: perspectives for a new class of drugs. Cardiovasc Hematol Agents Med Chem. 2008 Apr;6(2):80-91. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0336 mL | 10.1680 mL | 20.3360 mL | 50.8399 mL |
| 5 mM | 0.4067 mL | 2.0336 mL | 4.0672 mL | 10.1680 mL | |
| 10 mM | 0.2034 mL | 1.0168 mL | 2.0336 mL | 5.0840 mL | |
| 15 mM | 0.1356 mL | 0.6779 mL | 1.3557 mL | 3.3893 mL | |
| 20 mM | 0.1017 mL | 0.5084 mL | 1.0168 mL | 2.5420 mL | |
| 25 mM | 0.0813 mL | 0.4067 mL | 0.8134 mL | 2.0336 mL | |
| 30 mM | 0.0678 mL | 0.3389 mL | 0.6779 mL | 1.6947 mL |