sEH-IN-26
sEH-IN-26 is a urea structure-based soluble epoxide hydrolase (sEH) inhibitor with selectivity for mammalian cytosolic and peroxisomal sEH. sEH-IN-26 can be used for the research of inflammation and epoxide hydrolase-related diseases.
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- CAS 番号: 2222-58-4
- 分子式: C14H26N2O
- 分子量:238.37
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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sEH |
sEH-IN-26 (compound 57) potently inhibits soluble epoxide hydrolase, with an IC50 of 0.06 μM against mouse sEH and 0.16 μM against human sEH. It shows almost no inhibitory effect on rat microsomal mEH, with an IC50 greater than 500 μM, and exhibits extremely high subtype selectivity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2222-58-4
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分子量 238.37
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分子式 C14H26N2O
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SMILES
O=C(NC1CCCCC1)NCC2CCCCC2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)