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SIK2-IN-3

SIK2-IN-3 is an orally active SIK1/2 selective inhibitor (IC50: 0.128/0.084 μM). SIK2-IN-3 inhibits CRTC3 phosphorylation and myeloid cell pro-inflammatory cytokine production. SIK2-IN-3 ameliorates systemic and tissue inflammatory responses in a mouse anti-CD40 colitis model.

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  • CAS 番号: 2810809-10-8
  • 分子式: C23H24N6O2
  • 分子量:416.48
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • SIK2-IN-3 Chemical Structure
    SIK2-IN-3 構造式
CAS 番号: 2810809-10-8
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Salt-inducible Kinase (SIK) アイソフォーム固有の製品をすべて表示

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  • SIK2-IN-3 Chemical Structure
    SIK2-IN-3 Chemical Structure
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  • SIK2-IN-3