TMEM175 agonist 4
TMEM175 agonist 4 (Compound 276) is a TMEM175 agonist. TMEM175 agonist 4 can be used for the research of neurodegenerative diseases and lysosomal storage diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C22H22F2N4O2
- 分子量:412.43
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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TMEM175 138 nM (EC50) |
TMEM175 is a bifunctional channel protein located on the lysosomal membrane with permeability to both protons and potassium ions. It maintains lysosomal homeostasis and α-synuclein degradation, and its loss-of-function mutations significantly increase the risk of Parkinson's disease.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 412.43
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分子式 C22H22F2N4O2
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SMILES
FC(C1=C2CCCC1)=CN(C(C)C(NC3=CC=C(C4=C(F)C=NN4C)C=C3)=O)C2=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)