UPG-108
UPG-108, a peptide compound, is a non-competitive allosteric modulator of Urotensin II receptors (UTR). UPG-108 significantly enhances the efficacy of UTR agonists but reduces the potency of UTR agonists. UPG-111 efficiently induces calcium release and does not cause contraction of rat aortic rings without endothelial denudation. UPG-111 can be used to study various diseases related to the angiotensinergic system.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3090686-88-4
- 分子式: C65H88N14O17S2
- 分子量:1401.61
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
化学情報
-
CAS 番号 3090686-88-4
-
分子量 1401.61
-
分子式 C65H88N14O17S2
-
配列
Glu-Thr-Pro-Glu-Asp-{Pen}-Phe-{d-Trp}-{Orn}-Tyr-Cys-Val (Disulfide bridge: Pen-Cys)
-
シーケンスの短縮
ETPED-{Pen}-F-{d-Trp}-{Orn}-YCV (Disulfide bridge: Pen-Cys)
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
UPG-108 関連分類
HY-P11258 関連分類
Powered by Bioz
- UPG-108
- 3090686-88-4
- UPG108
- UPG 108
- Urotensin Receptor
- Urotensin II receptor (UTR)
- Super-agonist
- Positive allosteric modulator (PAM)
- Lateral allostery
- GPCR multimer
- Structure-activity relationship (SAR)
- N-terminal peptide engineering
- Noncompetitive modulation
- Calcium mobilization
- Rat aorta contraction
- Inhibitor
- inhibitor
- inhibit