Gstm1 - glutathione S-transferase mu 1 Gene

Also Known as GSTA3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24423

Summary

Enables several functions, including glutathione binding activity; glutathione transferase activity; and nickel cation binding activity. Involved in several processes, including response to ethanol; response to lead ion; and response to lithium ion. Located in cytosol and extracellular region. Part of protein-containing complex. Used to study cholestasis. Biomarker of hypertension and liver cirrhosis. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); gastrointestinal system Cancer (multiple); hematologic Cancer (multiple); and lung disease (multiple). Orthologous to human GSTM1 (Glutathione S-transferase mu 1). [provided by Alliance of Genome Resources, Apr 2022]

Gstm1 Products (1)

mRNA Protein Name
NM_017014.2 NP_058710.2 glutathione S-transferase Mu 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables glutathione binding IDA
IDA: Inferred from direct assay
17112229 RGD
enables glutathione transferase activity IDA
IDA: Inferred from direct assay
10229687 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
11015213 RGD
enables nickel cation binding IDA
IDA: Inferred from direct assay
7831282 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
23741294 RGD
enables steroid binding IPI
IPI: Inferred from physical interaction
10229687 RGD
Biological Process GO Annotation Evidence References Source
involved in glutathione metabolic process IDA
IDA: Inferred from direct assay
10229687 RGD
involved in glutathione metabolic process IMP
IMP: Inferred from mutant phenotype
12027896 RGD
involved in response to amino acid IEP
IEP: Inferred from expression pattern
11040448 RGD
involved in response to axon injury IEP
IEP: Inferred from expression pattern
20298122 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
22545783 RGD
involved in response to lead ion IEP
IEP: Inferred from expression pattern
9750042 RGD
involved in response to metal ion IEP
IEP: Inferred from expression pattern
23470461 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
18754104 RGD
involved in xenobiotic catabolic process IDA
IDA: Inferred from direct assay
17112229 RGD
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
17112229 RGD
located in extracellular region IDA
IDA: Inferred from direct assay
10229687 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
11015213 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutathione S-transferase Mu 1

  • GST 3-3

  • GST Yb1

  • GSTM1-1

  • glutathione S-transferase M1

  • glutathione S-transferase Yb-1 subunit

  • glutathione-S-transferase, mu type 1 (Yb1)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112534 GSTO-IN-2 Inhibitor 98.0% Unkown
HY-RS20418 Gstm1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05879 GSTM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26927 Gstm1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gstm1 NCBI NCBI:2944