Tnfsf12 - TNF superfamily member 12 Gene

Also Known as TWEAK; Tnlg4a

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 360548

Summary

Predicted to enable receptor ligand activity. Predicted to be involved in extrinsic apoptotic signaling pathway and positive regulation of extrinsic apoptotic signaling pathway. Predicted to act upstream of or within positive regulation of protein catabolic process. Predicted to be located in extracellular region and perinuclear region of cytoplasm. Predicted to be active in extracellular space. Orthologous to several human genes including TNFSF12-TNFSF13 (TNFSF12-TNFSF13 readthrough). [provided by Alliance of Genome Resources, Apr 2022]

Tnfsf12 Products (1)

mRNA Protein Name
NM_001001513.2 NP_001001513.2 tumor necrosis factor ligand superfamily member 12
Protein Preferred Names Protein Names

tumor necrosis factor ligand superfamily member 12

  • TNF-related weak inducer of apoptosis

  • tumor necrosis factor ligand 4a

  • tumor necrosis factor superfamily member 12

Recombinant Tnfsf12 Proteins

Cat. No. Product Name Accession Purity
HY-P77266 TWEAK/TNFSF12 Protein, Rat (HEK293, Fc) Q6AYC1 (R105-H249) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990657 RG-7212 (RO5458640) Inhibitor 99.62% Phase 1

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14822 TNFSF12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17099 Tnfsf12 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23543 Tnfsf12 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfsf12 NCBI NCBI:8742