UPG-111
UPG-111 is a peptide compound that acts as a negative allosteric modulator of the Urotensin II receptor (UTR). UPG-111 exhibits a dual inhibitory effect on the vasoconstriction induced by UTR agonists - it reduces both the maximum response intensity and the sensitivity of the agonist. UPG-111 does not induce calcium release or cause contraction of the endothelium-deprived rat aortic rings. UPG-111 can be used for the study of various diseases related to the angiotensinergic system.
For research use only. We do not sell to patients.
- CAS No.: 3090687-02-5
- Formula: C64H87N13O17S2
- Molecular Weight:1374.58
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Chemical Information
-
CAS No. 3090687-02-5
-
Molecular Weight 1374.58
-
Formula C64H87N13O17S2
-
Sequence
{hSer}-{TPED}-{Pen}-Phe-{d-Trp}-{Orn}-Tyr-Cys-Val (Disulfide bridge: Pen-Cys)
-
Sequence Shortening
{hSer}-{TPED}-{Pen}-F-{d-Trp}-{Orn}-YCV (Disulfide bridge: Pen-Cys)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UPG-111 Related Classifications
HY-P11259 Related Classifications
Powered by Bioz
- UPG-111
- 3090687-02-5
- UPG111
- UPG 111
- Urotensin Receptor
- Urotensin II receptor (UTR) modulators
- Negative allosteric modulator (NAM)
- Lateral allostery
- GPCR multimeric model
- Structure-activity relationship (SAR)
- N-terminal peptide engineering
- Noncompetitive antagonism
- Calcium mobilization
- Rat aorta contraction
- Inhibitor
- inhibitor
- inhibit