4-Bromo-7-azaindole
Based on 1 publication(s) in Google Scholar
4-Bromo-7-azaindole is a brominated derivative of 7-azaindole. 4-Bromo-7-azaindole serves as a substrate for palladium-catalyzed C-N and C-O cross-coupling reactions, reacting with amides, amines, amino acid esters and phenols.
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- Purity: 99.55%
- CAS No.: 348640-06-2
- 화학식: C7H5BrN2
- 분자량:197.03
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 4-Bromo-7-azaindole
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Biological Activity
As a key intermediate in pharmaceutical and organic synthesis, 4-Bromo-7-azaindole can be used to construct C-N and C-O bonds via palladium catalysis, and couples with amides, amines, amino acid esters, and phenols for the preparation of pharmacologically active molecules and kinase inhibitor scaffolds[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 348640-06-2
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Appearance Solid
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분자량 197.03
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화학식 C7H5BrN2
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Color White to light yellow
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SMILES
BrC1=CC=NC2=C1C=CN2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (1)
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Journal Impact Factor
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Most Recent
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Anal Chem
Exposome-Scale Investigation of Cl-/Br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multistage Machine Learning, and Cloud Computing. [Abstract]2025 Jun 3;97(21):11099-11109. PMID: 40401576
용액&용해도
DMSO : 25 mg/mL (126.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (277 KB)
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SDS (642 KB)
- English - EN (642 KB)
- Français - FR (642 KB)
- Deutsch - DE (642 KB)
- Norwegian - NO (642 KB)
- Español - ES (642 KB)
- Swedish - SV (642 KB)
- Italian - IT (642 KB)
- Korean - KR (642 KB)
- Portuguese - PT (642 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 5.0754 mL | 25.3768 mL | 50.7537 mL | 126.8842 mL |
| 5 mM | 1.0151 mL | 5.0754 mL | 10.1507 mL | 25.3768 mL | |
| 10 mM | 0.5075 mL | 2.5377 mL | 5.0754 mL | 12.6884 mL | |
| 15 mM | 0.3384 mL | 1.6918 mL | 3.3836 mL | 8.4589 mL | |
| 20 mM | 0.2538 mL | 1.2688 mL | 2.5377 mL | 6.3442 mL | |
| 25 mM | 0.2030 mL | 1.0151 mL | 2.0301 mL | 5.0754 mL | |
| 30 mM | 0.1692 mL | 0.8459 mL | 1.6918 mL | 4.2295 mL | |
| 40 mM | 0.1269 mL | 0.6344 mL | 1.2688 mL | 3.1721 mL | |
| 50 mM | 0.1015 mL | 0.5075 mL | 1.0151 mL | 2.5377 mL | |
| 60 mM | 0.0846 mL | 0.4229 mL | 0.8459 mL | 2.1147 mL | |
| 80 mM | 0.0634 mL | 0.3172 mL | 0.6344 mL | 1.5861 mL | |
| 100 mM | 0.0508 mL | 0.2538 mL | 0.5075 mL | 1.2688 mL |
4-Bromo-7-azaindole Related Classifications
HY-30014 Related Classifications
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