BTK-IN-22
BTK-IN-22 is a BTK inhibitor (IC50: 0.9 nM). BTK-IN-22 also inhibits BLX and BMX with IC50s of 1.4 and 1.2 nM respectively. BTK-IN-22 shows improved kinase selectivity compared to Ibrutinib (HY-10997)
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- CAS No.: 2573048-10-7
- 화학식: C26H26N6O2
- 분자량:454.52
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
BTK-IN-23 (Compound 2) inhibits BTK autophosphorylation in Jeko-1 cells, with an IC50 of 109 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Jeko-1 cell
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Concentration:0.01, 0.1, 1, 10 μM
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Incubation Time:2 h
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Result:Inhibited BTK autophosphorylation.
Chemical Information
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CAS No. 2573048-10-7
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분자량 454.52
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화학식 C26H26N6O2
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SMILES
CC(C=C(C=C1)OC2=CC=CC=C2)=C1C3=NN(C4=NC=NC(N)=C43)[C@@H]5CCCN(C5)C(C=C)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BTK-IN-22 Related Classifications
HY-148585 Related Classifications
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