2573048-10-7
Chemical Structure
BTK-IN-22
- CAS No.: 2573048-10-7
- Formula:C26H26N6O2
- Molecular Weight:454.52
IUPAC Name: (S)-1-(3-(4-amino-3-(2-methyl-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one
InChIKey: BJMXICGJKUALLN-GOSISDBHSA-N
SMILES: CC(C=C(C=C1)OC2=CC=CC=C2)=C1C3=NN(C4=NC=NC(N)=C43)[C@@H]5CCCN(C5)C(C=C)=O
Biological Activity: BTK-IN-22 is a BTK inhibitor (IC50: 0.9 nM). BTK-IN-22 also inhibits BLX and BMX with IC50s of 1.4 and 1.2 nM respectively. BTK-IN-22 shows improved kinase selectivity compared to Ibrutinib (HY-10997)[1]
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BTK-IN-22 | BTK-IN-22 is a BTK inhibitor (IC50: 0.9 nM). BTK-IN-22 also inhibits BLX and BMX with IC50s of 1.4 and 1.2 nM respectively. BTK-IN-22 shows improved kinase selectivity compared to Ibrutinib (HY-10997) | |||||||||||||||||||||
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Keywords