2573048-10-7

BTK-IN-22 Chemical Structure
2573048-10-7

Chemical Structure

BTK-IN-22

  • CAS No.: 2573048-10-7
  • Formula:C26H26N6O2
  • Molecular Weight:454.52

IUPAC Name: (S)-1-(3-(4-amino-3-(2-methyl-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

InChIKey: BJMXICGJKUALLN-GOSISDBHSA-N

SMILES: CC(C=C(C=C1)OC2=CC=CC=C2)=C1C3=NN(C4=NC=NC(N)=C43)[C@@H]5CCCN(C5)C(C=C)=O

Biological Activity: BTK-IN-22 is a BTK inhibitor (IC50: 0.9 nM). BTK-IN-22 also inhibits BLX and BMX with IC50s of 1.4 and 1.2 nM respectively. BTK-IN-22 shows improved kinase selectivity compared to Ibrutinib (HY-10997)[1]

Cat. No. Product Name Purity Description Pricing
HY-148585
BTK-IN-22 BTK-IN-22 is a BTK inhibitor (IC50: 0.9 nM). BTK-IN-22 also inhibits BLX and BMX with IC50s of 1.4 and 1.2 nM respectively. BTK-IN-22 shows improved kinase selectivity compared to Ibrutinib (HY-10997)
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