Desoxycarbadox-d3
Based on 1 publication(s) in Google Scholar
Desoxycarbadox-d3 is the deuterium labeled Desoxycarbadox. Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound.
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- Purity: 99.78%
- CAS No.: 1448350-02-4
- 화학식: C11H7D3N4O2
- 분자량:233.24
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보관:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Desoxycarbadox-d3
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1448350-02-4
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Unlabeled Cas 55456-55-8
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Appearance Solid
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분자량 233.24
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화학식 C11H7D3N4O2
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Color White to off-white
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SMILES
O=C(N/N=C/C1=NC2=CC=CC=C2N=C1)OC([2H])([2H])[2H]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Agric Food Chem
2025 Oct 1;73(39):25057-25064. PMID: 40968650
순도&문서
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Data Sheet (270 KB)
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SDS (768 KB)
- English - EN (768 KB)
- Français - FR (768 KB)
- Deutsch - DE (768 KB)
- Norwegian - NO (768 KB)
- Español - ES (768 KB)
- Swedish - SV (768 KB)
- Italian - IT (768 KB)
- Korean - KR (768 KB)
- Portuguese - PT (768 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. MacIntosh AI, et al. Liquid chromatographic monitoring of the depletion of carbadox and its metabolite desoxycarbadox in swine tissues. J Assoc Off Anal Chem. 1985;68(4):665-671. [Content Brief]
[3]. Looft T, et al. Carbadox has both temporary and lasting effects on the swine gut microbiota. Front Microbiol. 2014;5:276. Published 2014 Jun 10. [Content Brief]
[4]. Zhang K, et al. Investigation of quinocetone-induced mitochondrial damage and apoptosis in HepG2 cells and compared with its metabolites. Environ Toxicol Pharmacol. 2015;39(2):555-567. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Desoxycarbadox-d3 Related Classifications
HY-136428S Related Classifications
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