Epicorazine A
Epicorazine A has activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VRE), MICs of 12.5-25 μg/mL. Epicorazine A also has effect on Candida albicans with a MIC of 25 μg/mL.
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- CAS No.: 62256-05-7
- 화학식: C18H16N2O6S2
- 분자량:420.46
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
2.3 μM
Compound: 4
|
Cytotoxicity against human A549 cells after 24 hrs by SRB assay
Cytotoxicity against human A549 cells after 24 hrs by SRB assay
|
[PMID: 24370114] |
| HCT-116 | IC50 |
0.33 μM
Compound: 4
|
Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 24370114] |
| HL-60 | IC50 |
0.05 μM
Compound: 4
|
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
|
[PMID: 24370114] |
| K562 | IC50 |
1.5 μM
Compound: 4
|
Cytotoxicity against human K562 cells after 72 hrs by MTT assay
Cytotoxicity against human K562 cells after 72 hrs by MTT assay
|
[PMID: 24370114] |
| MGC-803 | IC50 |
2.7 μM
Compound: 4
|
Cytotoxicity against human MGC803 cells after 24 hrs by SRB assay
Cytotoxicity against human MGC803 cells after 24 hrs by SRB assay
|
[PMID: 24370114] |
Chemical Information
-
CAS No. 62256-05-7
-
분자량 420.46
-
화학식 C18H16N2O6S2
-
SMILES
O=C1[C@@]23N(C([C@@]4(SS3)N1[C@@]5([H])[C@](C(C=C[C@@H]5O)=O)([H])C4)=O)[C@@]6([H])[C@](C(C=C[C@@H]6O)=O)([H])C2
-
Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)