Ago3 - argonaute RISC catalytic subunit 3 Gene

Also Known as Eif2c3; C130014L07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 214150

Summary

Enables RNA binding activity. Involved in positive regulation of NIK/NF-kappaB signaling and positive regulation of gene expression. Located in condensed nuclear chromosome. Part of RISC complex. Is expressed in several structures, including central nervous system; early embryo; lung mesenchyme; sensory organ; and tooth. Orthologous to human AGO3 (argonaute RISC catalytic component 3). [provided by Alliance of Genome Resources, Apr 2022]

Ago3 Products (1)

mRNA Protein Name
NM_153402.2 NP_700451.2 protein argonaute-3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
19536157 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
26764146 MGI
involved in positive regulation of non-canonical NF-kappaB signal transduction IMP
IMP: Inferred from mutant phenotype
26764146 MGI
Cellular Component GO Annotation Evidence References Source
part of RISC complex IDA
IDA: Inferred from direct assay
19536157 MGI
located in condensed nuclear chromosome IDA
IDA: Inferred from direct assay
22863743 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein argonaute-3

  • Piwi/Argonaute family protein meIF2C3

  • argonaute 3

  • argonaute RISC catalytic component 3

  • argonaute3

  • eIF-2C 3

  • eIF2C 3

  • eukaryotic translation initiation factor 2C, 3

  • mAgo3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS00454 AGO3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20689 Ago3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27200 Ago3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ago3 NCBI NCBI:192669