PTGFRN - prostaglandin F2 receptor inhibitor Gene

Also Known as FPRP; CD315; EWI-F; CD9P-1; SMAP-6

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 5738

About PTGFRN

Cytogenetic location: 1p13.1 Genomic coordinates (GRCh38): 1:116,909,916-116,990,353 (from NCBI)

This gene has 3 transcripts (splice variants), 227 orthologues and 5 paralogues. Ubiquitous expression in heart (RPKM 21.3), endometrium (RPKM 18.0) and 24 other tissues.

Summary

Predicted to be involved in myoblast fusion involved in skeletal muscle regeneration. Predicted to act upstream of or within lipid droplet organization. Located in cell surface. [provided by Alliance of Genome Resources, Apr 2022]

PTGFRN Products (1)

mRNA Protein Name
NM_020440.4 NP_065173.2 prostaglandin F2 receptor negative regulator precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11278880 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PTGFRN Protein Structure

V-set

V-set: Immunoglobulin V-set domain (30 - 130)

Ig_2

Ig_2: Immunoglobulin domain (152 - 269)

V-set

V-set: Immunoglobulin V-set domain (283 - 376)

Ig_2

Ig_2: Immunoglobulin domain (417 - 528)

Ig_2

Ig_2: Immunoglobulin domain (562 - 659)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 879 a.a.
Protein Preferred Names Protein Names

prostaglandin F2 receptor negative regulator

  • CD9 partner 1

PTGFRN Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PTGFRN Q9P2B2 CD9 Homo sapiens P21926
Anti Bait CoIP
23091066
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant PTGFRN Proteins

Cat. No. 상품명 Accession Purity
HY-P77467 FPRP/PTGFRN Protein, Cynomolgus (HEK293, His) H9ERH4 (R22-K830) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P77889 FPRP/PTGFRN Protein, Human (HEK293, His) Q9P2B2 (V26-P832) ≥ 95%, as determined by Bis-Tris PAGE.

PTGFRN Antibodies

Cat. No. 상품명 신청 Reactivity
HY-P84847 CD315 Antibody (YA4544) IHC-P, FC, ELISA Human
HY-P84847A CD315 Antibody (YA4544)(PBS only) IHC-P, FC, ELISA Human

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS11385 PTGFRN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19523 Ptgfrn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26018 Ptgfrn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris PTGFRN VGNC VGNC:45148
Bos taurus PTGFRN VGNC VGNC:33508
Rattus norvegicus PTGFRN RGD RGD:3437
Macaca mulatta PTGFRN VGNC VGNC:76585
Felis catus PTGFRN VGNC VGNC:69144
Mus musculus PTGFRN MGD MGI:1277114
Others PTGFRN NCBI