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CD315 Antibody (YA4544)(PBS only)

(Synonyms: PTGFRN; FPRP; EWI-F; CD9P-1; SMAP-6)

CD315 Antibody (YA4544) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CD315.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2b

  • Application:

    IHC-P, FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • CD315 Antibody (YA4544)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:200-1:1000 1:200-1:400 1:10000

Product Details

Description

CD315 Antibody (YA4544) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CD315.

  • Host Mouse
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 99 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 99 kDa
Immunogen

Purified recombinant fragment of human CD315 (AA: extra 46-221) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG2b

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    CD315 inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur. In myoblasts, associates with tetraspanins CD9 and CD81 to prevent myotube fusion during muscle regeneration

  • Subcellular Localization

    Endoplasmic reticulum membrane; Single-pass type I membrane protein; Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein

  • Subunit

    Interacts with CD9 and CD81 (PubMed:11278880). Also seems to interact with CD63, CD82 and CD151 (PubMed:11278880)

  • SwissProt ID

    Q9P2B2

  • Gene ID
    5738 [NCBI]
  • Synonyms

    PTGFRN; FPRP; EWI-F; CD9P-1; SMAP-6

CD315 Antibody (YA4544)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • CD315 Antibody (YA4544)(PBS only) Product Image