Syt9 - synaptotagmin IX Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 60510

Summary

Enables SNARE binding activity; identical protein binding activity; and phospholipid binding activity. Involved in calcium-dependent activation of synaptic vesicle fusion and regulation of calcium ion-dependent exocytosis. Located in dense core granule. Is integral component of synaptic vesicle membrane. Is active in hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including adrenal gland; gonad; liver; nervous system; and spleen. Orthologous to human SYT9 (synaptotagmin 9). [provided by Alliance of Genome Resources, Apr 2022]

Syt9 Products (1)

mRNA Protein Name
NM_021889.4 NP_068689.2 synaptotagmin-9

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables SNARE binding IDA
IDA: Inferred from direct assay
12860971 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
10531343 MGI
enables phosphatidylinositol-4,5-bisphosphate binding IDA
IDA: Inferred from direct assay
12860971 MGI
enables phosphatidylserine binding IDA
IDA: Inferred from direct assay
12860971 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10531343 MGI
Biological Process GO Annotation Evidence References Source
involved in calcium-dependent activation of synaptic vesicle fusion IDA
IDA: Inferred from direct assay
17521570 MGI
involved in calcium-dependent activation of synaptic vesicle fusion IMP
IMP: Inferred from mutant phenotype
17521570 MGI
involved in regulation of calcium ion-dependent exocytosis IMP
IMP: Inferred from mutant phenotype
12860971 MGI
Cellular Component GO Annotation Evidence References Source
located in dense core granule IDA
IDA: Inferred from direct assay
16407767 MGI
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: Inferred from direct assay
17521570 MGI
is active in hippocampal mossy fiber to CA3 synapse IEP
IEP: Inferred from expression pattern
17521570 MGI
is active in hippocampal mossy fiber to CA3 synapse IMP
IMP: Inferred from mutant phenotype
17521570 MGI
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
17521570 MGI
is active in synaptic vesicle membrane IEP
IEP: Inferred from expression pattern
17521570 MGI
is active in synaptic vesicle membrane IMP
IMP: Inferred from mutant phenotype
17521570 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synaptotagmin-9

  • synaptotagmin V

  • sytIX

Syt9 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Syt9 Q9R0N9 Syt3 Mus musculus O35681
Comigration in SDS
10531343
Intra
Syt9 Q9R0N9 Syt10 Mus musculus Q9R0N4
Comigration in SDS
10531343
Intra
Syt9 Q9R0N9 Syt9 Mus musculus Q9R0N9
Comigration in SDS
10531343
Intra
Syt9 Q9R0N9 Wnk1 Rattus norvegicus Q9JIH7
Y2H
15350218
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS14121 SYT9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Syt9 NCBI NCBI:143425