Syt3 - synaptotagmin III Gene

Also Known as sytIII

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20981

Summary

Enables calcium-dependent phospholipid binding activity; protein heterodimerization activity; and protein homodimerization activity. Predicted to be involved in several processes, including positive regulation of dendrite extension; regulation of dopamine secretion; and regulation of vesicle-mediated transport. Predicted to act upstream of or within cell differentiation and exocytosis. Predicted to be located in endosome. Predicted to be active in exocytic vesicle and plasma membrane. Is expressed in several structures, including eye; genitourinary system; heart; nervous system; and respiratory system. Orthologous to human SYT3 (synaptotagmin 3). [provided by Alliance of Genome Resources, Apr 2022]

Syt3 Products (2)

mRNA Protein Name
NM_001114116.1 NP_001107588.1 synaptotagmin-3
NM_016663.3 NP_057872.3 synaptotagmin-3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium-dependent phospholipid binding IDA
IDA: Inferred from direct assay
8626542 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
10531343 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10531343 MGI
enables protein heterodimerization activity IPI
IPI: Inferred from physical interaction
20002670 MGI
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
10531343 MGI
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: Inferred from direct assay
30545844 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
IMP: Inferred from mutant phenotype
30545844 MGI
Cellular Component GO Annotation Evidence References Source
is active in postsynapse IDA
IDA: Inferred from direct assay
30545844 MGI
is active in postsynapse IEP
IEP: Inferred from expression pattern
30545844 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synaptotagmin-3

Syt3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Syt3 O35681 Syt10 Mus musculus Q9R0N4
Comigration in SDS
10531343
Intra
Syt3 O35681 Syt9 Mus musculus Q9R0N9
Comigration in SDS
10531343
Intra
Syt3 O35681 Syt3 Mus musculus O35681
Comigration in SDS
10531343
Intra
Syt3 O35681 Syt6 Mus musculus Q9R0N8
Comigration in SDS
10531343
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P2259 TAT-GluA2 3Y Inhibitor 99.93% Unkown
HY-RS14115 SYT3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Syt3 NCBI NCBI:84258