Syt10 - synaptotagmin X Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54526

Summary

Enables several functions, including SNARE binding activity; phospholipid binding activity; and protein dimerization activity. Involved in chemical synaptic transmission; positive regulation of calcium ion-dependent exocytosis; and sensory perception of smell. Located in exocytic vesicle. Is expressed in several structures, including alimentary system; brain; cardiovascular system; ear; and skeleton. Orthologous to human SYT10 (synaptotagmin 10). [provided by Alliance of Genome Resources, Apr 2022]

Syt10 Products (1)

mRNA Protein Name
NM_018803.2 NP_061273.1 synaptotagmin-10

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables SNARE binding IDA
IDA: Inferred from direct assay
12860971 MGI
enables calcium ion binding IMP
IMP: Inferred from mutant phenotype
21496647 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
10531343 MGI
enables phosphatidylinositol-4,5-bisphosphate binding IDA
IDA: Inferred from direct assay
12860971 MGI
enables phosphatidylserine binding IDA
IDA: Inferred from direct assay
12860971 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10531343 MGI
enables protein heterodimerization activity IPI
IPI: Inferred from physical interaction
10531344 MGI
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
10531343 MGI
Biological Process GO Annotation Evidence References Source
involved in chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
21496647 MGI
involved in positive regulation of calcium ion-dependent exocytosis IMP
IMP: Inferred from mutant phenotype
21496647 MGI
involved in presynaptic dense core vesicle exocytosis IDA
IDA: Inferred from direct assay
28683263 MGI
involved in presynaptic dense core vesicle exocytosis IMP
IMP: Inferred from mutant phenotype
28683263 MGI
involved in regulation of calcium ion-dependent exocytosis IMP
IMP: Inferred from mutant phenotype
12860971 MGI
involved in sensory perception of smell IMP
IMP: Inferred from mutant phenotype
21496647 MGI
NOT involved in synaptic vesicle exocytosis IMP
IMP: Inferred from mutant phenotype
21496647 MGI
Cellular Component GO Annotation Evidence References Source
located in exocytic vesicle IDA
IDA: Inferred from direct assay
21496647 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
28683263 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
28683263 MGI
is active in presynapse IDA
IDA: Inferred from direct assay
28683263 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synaptotagmin-10

  • sytX

Syt10 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Syt10 Q9R0N4 Syt3 Mus musculus O35681
Comigration in SDS
10531343
Intra
Syt10 Q9R0N4 Syt9 Mus musculus Q9R0N9
Comigration in SDS
10531343
Intra
Syt10 Q9R0N4 Syt10 Mus musculus Q9R0N4
Comigration in SDS
10531343
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14107 SYT10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Syt10 NCBI NCBI:341359