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Cat. No.: HY-162533

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GSPT1 degrader-4

GSPT1 degrader-4 (3) is a GSPT1 molecule glue (DC₅₀ of 25.4 nM), with an IC₅₀ of 39 nM for CAL51 proliferation.

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CAS No.: 3034764-32-1
화학식: C₂₄H₂₁ClN₄O₅
분자량:480.90

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

GSPT1 degrader-4 Chemical Structure

CAS No.: 3034764-32-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

GSPT1 degrader-4 (3) is a GSPT1 molecule glue (DC₅₀ of 25.4 nM), with an IC₅₀ of 39 nM for CAL51 proliferation^[1].

Chemical Information

CAS No. 3034764-32-1
분자량 480.90
화학식 C₂₄H₂₁ClN₄O₅
SMILES

CC1=CC=C(NC(OCC2=CC=C3C(C=C(CN4C5C(NC(CC5)=O)=O)N3C4=O)=C2)=O)C=C1Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jinghai, Jin, et al. Fused ring compound, pharmaceutical composition, and use thereof. Patent. WO2024067792A1.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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