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Cat. No.: HY-12712

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L-657743

L-657743 is a highly potent, highly selective, and orally active α₂-adrenoceptor antagonist. L-657743 can be used in the research of neurological diseases such as depression.

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CAS No.: 111466-41-2
화학식: C₂₀H₂₅N₃O₂
분자량:339.43

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

L-657743 Chemical Structure

CAS No.: 111466-41-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- IC₅₀ & Target
Chemical Information
순도&문서
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Biological Activity

제품 설명

L-657743 is a highly potent, highly selective, and orally active α₂-adrenoceptor antagonist. L-657743 can be used in the research of neurological diseases such as depression^[1].

IC₅₀ & Target^[1]

α2-adrenergic receptor

All Adrenergic Receptor Isoforms :

Chemical Information

CAS No. 111466-41-2
분자량 339.43
화학식 C₂₀H₂₅N₃O₂
SMILES

O=C1N(C)[C@]2(CCN1C)CCN3CCC4=C(OC5=CC=CC=C54)[C@]3([H])C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pettibone DJ, et al. Pharmacological profile of a new potent and specific alpha 2-adrenoceptor antagonist, L-657,743. Naunyn Schmiedebergs Arch Pharmacol. 1987 Aug;336(2):169-75. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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L-657743

All Adrenergic Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

L-657743 Related Classifications

HY-12712 Related Classifications