Oligopeptide-10
Based on 1 Customer Validation
Oligopeptide-10 is a bioactive peptide with antimicrobial activity. Oligopeptide-10 exhibits broad-spectrum bactericidal effects against Gram-positive bacteria including Propionibacterium acnes and Staphylococcus aureus. Oligopeptide-10 targets lipoteichoic acid (LTA) on the surface of bacterial cell membranes, induces bacterial osmotic imbalance by disrupting the integrity of bacterial membranes, and reduces the release of pro-inflammatory cytokines induced by bacteria. Oligopeptide-10 possesses skin-protective activity. Oligopeptide-10 can be applied in research related to acne vulgaris, dandruff, seborrheic dermatitis, and tinea pedis.
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- Purity: 99.91%
- CAS No.: 466691-40-7
- 화학식: C78H140N20O15
- 분자량:1598.07
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보관:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
Oligopeptide-10 exhibits broad-spectrum bactericidal effects against Gram-positive bacteria including Propionibacterium acnes and Staphylococcus aureus[1][3].
Oligopeptide-10 exhibits no cytotoxicity, irritation, sensitization, or mutagenicity in in vitro safety evaluations[1].
Oligopeptide-10 binds to lipoteichoic acid (LTA) on the bacterial surface, exerts antimicrobial activity, neutralizes pro-inflammatory bacterial components and reduces inflammatory responses[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 466691-40-7
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Appearance Solid
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분자량 1598.07
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화학식 C78H140N20O15
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Color White to off-white
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Sequence
Phe-Ala-Lys-Ala-Leu-Lys-Ala-Leu-Leu-Lys-Ala-Leu-Lys-Ala-Leu-NH2
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Sequence Shortening
FAKALKALLKALKAL-NH2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
용액&용해도
DMSO : 100 mg/mL (62.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6258 mL | 3.1288 mL | 6.2575 mL | 15.6439 mL |
| 5 mM | 0.1252 mL | 0.6258 mL | 1.2515 mL | 3.1288 mL | |
| 10 mM | 0.0626 mL | 0.3129 mL | 0.6258 mL | 1.5644 mL | |
| 15 mM | 0.0417 mL | 0.2086 mL | 0.4172 mL | 1.0429 mL | |
| 20 mM | 0.0313 mL | 0.1564 mL | 0.3129 mL | 0.7822 mL | |
| 25 mM | 0.0250 mL | 0.1252 mL | 0.2503 mL | 0.6258 mL | |
| 30 mM | 0.0209 mL | 0.1043 mL | 0.2086 mL | 0.5215 mL | |
| 40 mM | 0.0156 mL | 0.0782 mL | 0.1564 mL | 0.3911 mL | |
| 50 mM | 0.0125 mL | 0.0626 mL | 0.1252 mL | 0.3129 mL | |
| 60 mM | 0.0104 mL | 0.0521 mL | 0.1043 mL | 0.2607 mL |
Oligopeptide-10 Related Classifications
HY-P5255 Related Classifications
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