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Cat. No.: HY-161567

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OX2R-IN-3

OX2R-IN-3 (Compound 53) is an orally active type 2 orexin receptor (OX2R) agonist (EC₅₀<100 nM.).

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CAS No.: 2791360-37-5
화학식: C₂₄H₃₀F₃N₃O₃S
분자량:497.57

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

OX2R-IN-3 Chemical Structure

CAS No.: 2791360-37-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vivo
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

OX2R-IN-3 (Compound 53) is an orally active type 2 orexin receptor (OX2R) agonist (EC₅₀<100 nM.)^[1].

IC₅₀ & Target

OX₂ Receptor

<100 nM (EC₅₀)

All Orexin Receptor (OX Receptor) Isoforms :

In Vivo

OX2R-IN-3 (P.O.; 3 mg/kg; single dose) increases mean cortical activation time in SD rats by 105.00 %^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2791360-37-5
분자량 497.57
화학식 C₂₄H₃₀F₃N₃O₃S
SMILES

O=S(N[C@H]1CCN(C2=NC=CC=C2)C[C@H]1CO[C@@H](CC3)CC[C@@H]3C4=CC=CC=C4)(C(F)(F)F)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pennington, Lewis D, et al. Preparation of substituted piperidino compounds and related methods of treatment. United States, US20220194926 A1 2022-06-23

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vivo
Chemical Information
순도&문서
References

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OX2R-IN-3

All Orexin Receptor (OX Receptor) Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

OX2R-IN-3 Related Classifications

HY-161567 Related Classifications