PKM2 activator 7
PKM2 activator 7 (Compd B4) is a PKM2 activator with the AC50 of 0.144 μM. PKM2 activator 7 suppresses DSS (HY-116282C)-induced colitis by inhibiting T cell growth in mouse colitis model.
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- 화학식: C16H19F3O4
- 분자량:332.31
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| T-cell | IC50 |
0.43 μM
Compound: B4
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Antiproliferative activity against concanavalin A-stimulated C57BL/6 mouse T cells measured after 48 hrs by CCK8 assay
Antiproliferative activity against concanavalin A-stimulated C57BL/6 mouse T cells measured after 48 hrs by CCK8 assay
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[PMID: 38718622] |
Chemical Information
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분자량 332.31
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화학식 C16H19F3O4
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SMILES
C=C([C@H]1[C@H](O2)[C@H]3[C@@](O3)(C)CC/C=C(COC(F)(F)F)\CC1)C2=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PKM2 activator 7 Related Classifications
HY-161519 Related Classifications
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