Natural Product Library Plus

92 Cited Publications
고객리뷰

Based on 92 publication(s) in Google Scholar

Natural products are small molecules produced naturally by any organism including primary and secondary metabolites. Natural sources may lead to basic research on potential bioactive components for commercial development as lead compounds in drug discovery.

Nature has been a source of medicinal agents for thousands of years, and an impressive number of modern drugs have been isolated from natural sources, many based on their use in traditional medicine. With the development of new molecular targets, there is an increasing demand for novel molecular diversity for screening. Natural products will play a crucial role in meeting this demand through the continued investigation of world’s bio-diversity, much of which remains unexplored.

MCE provides a unique collection of 6,253 natural compounds that contains Saccharides and Glycosides, Phenylpropanoids, Quinones, Flavonoids, Terpenoids and Glycosides, Steroids, Alkaloid, Phenols, Acids and Aldehydes. Natural Product Library Plus, with more powerful screening capability, further complements Natural Product Library (HY-L021) by adding some compounds with low solubility or solution stability (Part B) to this library. All those supplementary are supplied in powder form.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

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Service

Description & Advantages

•   A unique collection of 6,253 natural products for high throughput screening (HTS) and high content screening (HCS).

•   The compounds in the library contain Saccharides and Glycosides, Phenylpropanoids, Quinones, Flavonoids, Terpenoids and Glycosides, Steroids, Alkaloid, Phenols, Acids andAldehydes.

•   A useful tool for drug discovery as an important source of lead compounds.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

  Part A Part B Part C
Number 5026 1227 0
Feature General natural product(HY-L021) Compounds with low solubility or stability Novel, rare or exclusive compounds
Package Solution (10 mM) or solid (1 mg) Only solid (1 mg) Only solid (1 mg)

Product Details

Formulation

A collection of 6,253 natural products supplied as pre-dissolved Solutions or Solid

Solution: 4,857 compounds supplied in 10 mM solution, 126 compounds supplied in 2 mM solution, 43 compounds supplied in 3 mg/mL solution.

Layout

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates.
This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage
-80°C
Shipping
Blue ice or dry ice

Documentation

  • PDF
  • Excel
  • SDF
  • Manual

Composition

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