SLR080811
SLR080811 is a guanidine-based selective sphingosine kinase 2 (SphK2) inhibitor with a Ki of 1.3 μM, exhibiting ~10-fold selectivity over SphK1 (Ki = 12 μM). SLR080811 reduces sphingosine 1-phosphate (S1P) levels in vitro, but drives a SphK1-dependent increase in S1P in mice. SLR080811 can be used for cancers and fibrosis research.
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- CAS No.: 1449765-65-4
- 화학식: C21H31N5O
- 분자량:369.50
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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SphK2 1.3 μM (Ki) |
SphK1 12 μM (Ki) |
Chemical Information
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CAS No. 1449765-65-4
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분자량 369.50
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화학식 C21H31N5O
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SMILES
N=C(N1[C@@H](C2=NC(C3=CC=C(C=C3)CCCCCCCC)=NO2)CCC1)N
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SLR080811 Related Classifications
HY-12896 Related Classifications
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